Each vaccine entry links to the manufacturer’s package insert that contains information about dosage, ingredient quantity, and how the vaccine is made. Long-term efficacy of hepatitis B vaccine, booster policy, and impact of hepatitis B virus mutant. Long-term efficacy of hepatitis B vaccine, booster policy, and impact of hepatitis B virus mutant. Dosage and Administration, Preparation for Administration X/XXXX ... 42 hepatitis B-containing vaccine, or to any component of TWINRIX, including yeast and 43 . Accessed 10/07/2018. COVID-19: The number of recommended doses shall be in accordance with the Hepatitis B vaccine recombinant is used to prevent infection by the hepatitis B virus. Source: U.S. National Library of Medicine. vaccine. Risk of anaphylaxis after vaccination of children and adolescents. And the last phase, the Phase III, is normally done in several thousand individuals, tens of thousands of individuals. Monitor for anaphylaxis and syncope, 15 minutes after administration. Influenza: Annual dose of inactivated influenza vaccine or live attenuated influenza vaccine. Anon. Expand year-round vaccination efforts with these resources, videos, and tools. Children. Bohlke K, Davis RL, Marcy SM, et al. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. Hepatitis B is caused by hepatitis B virus (HBV), and is spread by contact with body fluids, such as blood, saliva, semen, or vaginal fluids; by needle sticks or sharing needles; or from mother to child. Dosage, and timing of boosters varies by individual COVID-19 vaccine product. Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. The book presents ways to reduce the numbers of new HBV and HCV infections and the morbidity and mortality related to chronic viral hepatitis. *Infants whose mothers are HBsAg+ or whose HBsAg status is unknown should receive the third dose at 6 months of age +An additional dose at 4 months is acceptable if the clinician prefers to use a combination vaccine that contains hepatitis B vaccine Found inside – Page 14First dose within 1 week ; second and third doses , 1 and 6 months later . § See text for details . Less than 10 SRU by RIA , negative by EIA . 1. Exposed person not previously vaccinated . Hepatitis B vaccination should be considered ... Copyright © 2021 MIMS. Avoid use of salicylates for 6 weeks following administration of VARIVAX to children and adolescents. Vaccination can commence at Heplisav-B is the only two-dose hepatitis B vaccine approved for adults and is given over one month. Engerix-B requires three shots over a six-month period. Engerix-B requires three shots over a six-month period. patient receiving chemotherapy or immunosuppressants). Revising the manual has been a team exercise. There are contributions from a large number of experts, organizations and institutions. This new edition has seven modules. Varicella vaccine virus transmission may occur between vaccine recipients and contacts susceptible to varicella including healthy individuals. | MERCK & CO., INC. (USA). Accessed 10/07/2018. Copyright © 2021 MIMS Pte Ltd. All rights reserved. Antibodies are found in the bloodstream and are produced when the body detects a virus invading it. Cardell K, Akerlind B, Sallberg M, et al. doses of Engerix-B and Recombivax HB . Hypersensitivity. Both formulations may contain yeast proteins. Symptoms of hepatitis B include fever, yellowish skin (jaundice), dark urine, fatigue, nausea, and vomiting. The vaccine contains 720 EL.U. Lexicomp Online. Cardell K, Akerlind B, Sallberg M, et al. Hepatitis B vaccine is available for all age groups to prevent HBV infection. Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. Infants are recommended to receive 4 doses of hepatitis B vaccine: 1 dose of monovalent paediatric formulation hepatitis B vaccine at birth ; 3 doses of a paediatric hepatitis B–containing vaccine at 2, 4 and 6 months of age (usually provided as DTPa-hepB-IPV-Hib [diphtheria-tetanus-acellular pertussis, hepatitis B, inactivated poliovirus, Haemophilus influenzae type b]). Each vaccine entry links to the manufacturer’s package insert that contains information about dosage, ingredient quantity, and how the vaccine is made. Hepatitis B vaccine recombinant is used to prevent infection by the hepatitis B virus. Adult: Primary immunisation as recombinant hepatitis B surface antigen: 20 mcg for 3 doses given at 0, 1, and 6 months.Alternatively, or for patients known or presumed exposed to HBV: 20 mcg for 3 doses given at 0, 1, and 2 months followed by a booster at 12 months as accelerated dose schedule. The final dose in the infant series should not be given earlier … The hepatitis B vaccine The hepatitis B vaccine is one of the most effective ways to prevent hepatitis B. It’s usually divided into three doses, which are given over the course of six months. Withdraw the entire contents into the syringe, inject the total volume (approximately 0.5 mL) of reconstituted vaccine subcutaneously, and discard vial. Each 0.5 mL dose is administered subcutaneously. Recombivax HB Dialysis Formulation(R): Predialysis patients: Three doses (40 mcg/1 mL each), IM, on a 0, 1, and 6 month schedule Engerix-B(R) and Heplisav-B(R): Data not available. Immunocompromised patients: Primary immunisation: Same as adult dose. DailyMed. ¶ Hepatitis B vaccine **A responder is a person with adequate levels of serum antibody to HBsAg (i.e., anti-HBs >10 mlU/mL). Adult: Primary immunisation as recombinant hepatitis B surface antigen: 20 mcg for 3 doses given at 0, 1, and 6 months.Alternatively, or for patients known or presumed exposed to HBV: 20 mcg for 3 doses given at 0, 1, and 2 months followed by a booster at 12 months as accelerated dose schedule. COVID-19: The number of recommended doses shall be in accordance with the Hudson, Ohio. Vaccination with VARIVAX may not result in protection of all healthy, susceptible children, adolescents, and adults. (877.829.6372), Phone: 877.VAX.MERCK Renal Dose Adjustments. † Hepatitis B surface antigen § Hepatitis B immune glob ulin; dose is 0.06 mL/kg intramuscularly. *Infants whose mothers are HBsAg+ or whose HBsAg status is unknown should receive the third dose at 6 months of age +An additional dose at 4 months is acceptable if the clinician prefers to use a combination vaccine that contains hepatitis B vaccine The Hepatitis B vaccine is a series of inoculations that stimulate the body’s immune system to shield against the Hepatitis B virus. Dosage and Administration. Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. vaccine. Coauthored by Paul Offit, a member of the CDC advisory committee that determines which vaccines are recommended for use in the United States, this guide tells you what vaccines are made of and clearly explains how they are made, how they ... Immune Globulins and other blood products should not be given concomitantly with VARIVAX. To minimize loss of potency, administer VARIVAX immediately after reconstitution. Excellent response rate to a double dose of the combined hepatitis A and B vaccine in previous nonresponders to hepatitis B vaccine. Hepatitis B Vaccines. In the United States, Twinrix is licensed for use in people who are age 18 years or older. † Hepatitis B surface antigen § Hepatitis B immune glob ulin; dose is 0.06 mL/kg intramuscularly. Found inside – Page 221Several vaccine manufacturers have produced combination vaccines containing a hepatitis B vaccine component. ... first dose stored for up to 1 month at tropical temperatures.422 The excellent heat stability of hepatitis B vaccine allows ... Bohlke K, Davis RL, Marcy SM, et al. Hepatitis B vaccine recombinant is made without any human blood or blood products or any other substances of human origin. Accessed 10/07/2018. 2008. Heplisav-B is the only two-dose hepatitis B vaccine approved for adults and is given over one month. ††A nonresponder is a person with inadequate response to vaccination (i.e., serum anti-HBs <10 mlU/mL). The final dose in the infant series should not be given earlier … Engerix-B requires three shots over a six-month period. There must be at least 4 weeks between doses #1 and #2, at least 8 weeks between doses #2 and #3, and at least 16 weeks between doses #1 and #3. Heplisav-B demonstrated a statistically significantly higher rate of protection (95%) after one month when compared with Engerix-B (81%) after 6 months. 7. Buckingham R (ed). Journal of Infectious Diseases 198(3): 299–304. Risk of anaphylaxis after vaccination of children and adolescents. -Administer hepatitis B immune globulin if appropriate.-Start hepatitis B vaccine as soon as possible after exposure. The 2003 Red Book, 26th Edition advances the Red Book's mission for the 21st century, with the most current information on clinical manifestations, etiology, epidemiology, diagnosis, and treatment of more than 200 childhood infectious ... THE ESSENTIAL WORK IN TRAVEL MEDICINE -- NOW COMPLETELY UPDATED FOR 2018 As unprecedented numbers of travelers cross international borders each day, the need for up-to-date, practical information about the health challenges posed by travel ... Lexicomp Online. The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to ... Once the vaccine is administered, antibodies are produced to shield the person against the virus. Antibodies are found in the bloodstream and are produced when the body detects a virus invading it. Developed by the AAP (American Academy of Pediatrics) Committee on Infectious Diseases in conjunction with the CDC (Centers for disease control), the FDA (Food and drug administration), and other leading institutions with contributions from ... Each 0.5 mL dose is administered subcutaneously. 2008. Engerix B: 1 mL (20 mcg) IM at 0, 1, and 6 months; Recombivax HB: 1 mL (10 mcg) IM at 0, 1, and 6 months; Heplisav-B: Can be used as a substitute in a 3-dose series with a different hepatitis B vaccine This 2020 edition includes: · Country-specific risk guidelines for yellow fever and malaria, including expert recommendations and 26 detailed, country-level maps · Detailed maps showing distribution of travel-related illnesses, including ... The Patient Information also is available. A service brought to you by Merck & Co., Inc. Merck does not review or control the content at the site to which this link connects. Phone: 877.VAX.MERCK -Administer hepatitis B immune globulin if appropriate.-Start hepatitis B vaccine as soon as possible after exposure. Hepatitis B vaccine is available for all age groups to prevent HBV infection. ENGERIX-B [Hepatitis B Vaccine (Recombinant)] is a noninfectious recombinant DNA hepatitis B vaccine developed and manufactured by GlaxoSmithKline Biologicals. Infants are recommended to receive 4 doses of hepatitis B vaccine: 1 dose of monovalent paediatric formulation hepatitis B vaccine at birth ; 3 doses of a paediatric hepatitis B–containing vaccine at 2, 4 and 6 months of age (usually provided as DTPa-hepB-IPV-Hib [diphtheria-tetanus-acellular pertussis, hepatitis B, inactivated poliovirus, Haemophilus influenzae type b]). Vaccine 2005;23(31):4082-87. Due to the concern for transmission of vaccine virus, vaccine recipients should attempt to avoid, whenever possible, close association with susceptible high-risk individuals for up to 6 weeks following vaccination. This information is not country-specific. Each 0.5 mL dose is administered subcutaneously. Some vaccines, like influenza (flu) vaccines, are modified frequently and you may wish to consult your doctor’s office or pharmacy for the most current information. The new 8th Edition provides a single place to look for the most recent and most trustworthy recommendations on quality care of pregnant women, their fetuses, and their neonates. Accessed 10/07/2018. ENGERIX-B [Hepatitis B Vaccine (Recombinant)] is a noninfectious recombinant DNA hepatitis B vaccine developed and manufactured by GlaxoSmithKline Biologicals. Dosage, and timing of boosters varies by individual COVID-19 vaccine product. Primary liver cancer is a rather unusual malignancy in that the incidence varies tremendously from one geographical area to another. Vaccine 2005;23(31):4082-87. Guide your vaccination process with ideas for improvement. And the last phase, the Phase III, is normally done in several thousand individuals, tens of thousands of individuals. Screening for hepatitis B is recommended in pregnant … Utilize electronic health record (EHR) capabilities to help improve vaccination rates. An urgent effort is required if this situation is to be corrected. This Guide is intended to help those responsible for providing services aimed at reducing the burden posed by cervical cancer for women, communities and health systems. For Product Information and Consumer Medicine Information about Engerix-B visit the Therapeutic Goods Administration website.. For detailed advice on vaccine dosage, administration, contraindications and precautions, and variations from product information, please visit the relevant disease chapter/s. Hepatitis B: Three doses of hepatitis B vaccine, the first two given one month apart and the third given five months after the second. VARIVAX is a vaccine indicated for active immunization for the prevention of varicella in individuals 12 months of age or older. VARIVAX is administered as an approximately 0.5-mL dose by subcutaneous injection into the outer aspect of the upper arm (deltoid region) or the anterolateral thigh. Identify product codes and reimbursement information. Long-term efficacy of hepatitis B vaccine, booster policy, and impact of hepatitis B virus mutant. Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. There are insufficient data to assess the rate of protection of VARIVAX against the serious complications of chickenpox in adults (eg, encephalitis, hepatitis, pneumonia), and during pregnancy (congenital varicella syndrome). Background: Antibodies against hepatitis B surface antigen (HBsAg) wane over time following hepatitis B immunisation; hence, it is unclear whether people vaccinated in three-dose or four-dose schedules of the hepatitis B vaccine are still immune when the hepatitis B surface antibody (anti-HBs) level in their body is undetectable, or lower than the level usually considered protective. Hepatitis B Vaccine (Recombinant). 2003. The aim of this Maternal Immunization book is to provide a contemporary overview of vaccines used in pregnancy (and the lactation period), with emphasis on aspects of importance for the target groups, namely, rationale for the use of ... Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Hepatitis B is spread through person-to-person contact or through personal items like razors, toothbrushes, etc. It contains purified surface antigen of the virus obtained by culturing genetically engineered Saccharomyces cerevisiae cells, which carry the surface antigen gene of the hepatitis B virus. Both formulations may contain yeast proteins. Hepatitis B is a serious disease caused by a virus that attacks the liver. FitzSimons D, François G, Hall A et al. Vaccine 2005;23(31):4082-87. Hepatitis B is a serious disease caused by a virus that attacks the liver. Hepatitis B Immunization 3-dose series. Booster dose: 10 mcg every 6-12 months. Heplisav-B demonstrated a statistically significantly higher rate of protection (95%) after one month when compared with Engerix-B (81%) after 6 months. The second dose is administered between 4 … There is no drug to cure hepatitis B; however, there is a hepatitis B vaccine available. Vaccine 2005;23(31):4082-87. Help support your patients with informational materials and office tools. There is no drug to cure hepatitis B; however, there is a hepatitis B vaccine available. (877.829.6372). Pharmaceutical Press. This section contains information intended for health care professionals in the United States only and is not intended for the general public. of hepatitis A antigen (half of the Havrix adult dose) and 20 mcg of hepatitis B antigen (the full Engerix-B adult dose). The AAP's authoritative guide on preventing, recognizing, and treating more than 200 childhood infectious diseases. Engerix B: 1 mL (20 mcg) IM at 0, 1, and 6 months; Recombivax HB: 1 mL (10 mcg) IM at 0, 1, and 6 months; Heplisav-B: Can be used as a substitute in a 3-dose series with a different hepatitis B vaccine Hepatitis B is a contagious liver infection. Hepatitis B is spread through person-to-person contact or through personal items like razors, toothbrushes, etc. Patient with bleeding disorders including thrombocytopaenia, altered immunocompetence (e.g. Once the vaccine is administered, antibodies are produced to shield the person against the virus. To reconstitute the vaccine, first withdraw the total volume of provided sterile diluent into a syringe. All rights reserved. For Product Information and Consumer Medicine Information about Engerix-B visit the Therapeutic Goods Administration website.. For detailed advice on vaccine dosage, administration, contraindications and precautions, and variations from product information, please visit the relevant disease chapter/s. Hepatitis B virus (HBV) is a partly double-stranded DNA virus that causes acute and chronic liver infection. Hepatitis B is caused by hepatitis B virus (HBV), and is spread by contact with body fluids, such as blood, saliva, semen, or vaginal fluids; by needle sticks or sharing needles; or from mother to child. Phone: 877.VAX.MERCK In the United States, Twinrix is licensed for use in people who are age 18 years or older. The second dose is administered between 4 … Duval B, Gîlca V, Boulianne N et al. Dosage and Administration. VARIVAX is contraindicated for use in pregnant women because the vaccine contains live, attenuated varicella virus, and it is known that wild-type varicella virus, if acquired during pregnancy, can cause congenital varicella. Each 0.5 mL dose is administered subcutaneously. (Human Papillomavirus 9-valent Vaccine, Recombinant), (Measles, Mumps, and Rubella Virus Vaccine Live), [Haemophilus b Conjugate Vaccine (Meningococcal Protein Conjugate)], (Measles, Mumps, Rubella and Varicella Virus Vaccine Live), (Rotavirus Vaccine, Live, Oral, Pentavalent), (Diphtheria and Tetanus Toxoids and Acellular Pertussis, Inactivated Poliovirus, Haemophilus b Conjugate and Hepatitis B Vaccine), (Pneumococcal 15-valent Conjugate Vaccine). Vaccine 2005;23(31):4082-87. Hepatitis B vaccine should be deferred for infants with a birth weight <2,000 g if the mother is documented to be HBsAg negative at the time of the infant’s birth. The Final (3rd or 4th) dose in the Hepatitis B vaccine series should be administered no earlier than age 24 weeks, and at least 16 weeks after the first dose; A total of 4 doses of Hepatitis B vaccine is recommended when a combination vaccine containing Hepatitis B is administered after the birth dose; Catch-up vaccination (877.829.6372), Copyright © 2021 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc. All rights reserved. COVID-19: The number of recommended doses shall be in accordance with the A comprehensive reference covering all aspects of the clinical management of adult and child dialysis patients. This edition includes seven new chapters including one on EPO use in dialysis patients and one on the HIV positive patient. Hepatitis B vaccine is available for all age groups to prevent HBV infection. And the last phase, the Phase III, is normally done in several thousand individuals, tens of thousands of individuals. Protect from light. The vaccine works by causing your body to produce its own protection (antibodies) against the disease. Risk of bleeding with anticoagulants. In the United States, Twinrix is licensed for use in people who are age 18 years or older. Vaccination can commence at Martindale: The Complete Drug Reference [online]. Hepatitis B Immunization 3-dose series. Hepatitis B vaccine should be deferred for infants with a birth weight <2,000 g if the mother is documented to be HBsAg negative at the time of the infant’s birth. Found inside – Page 330If a low dosage of vaccine is administered, the dose should be repeated with the appropriate dosage. Administration of hepatitis B vaccines Hepatitis B vaccine should be administered intramuscularly, in the anterior thigh in children ... A boost in antibody levels has been observed in vaccinees following exposure to wild-type varicella, which could account for the apparent long-term persistence of antibody levels in these studies. Recombivax HB Dialysis Formulation(R): Predialysis patients: Three doses (40 mcg/1 mL each), IM, on a 0, 1, and 6 month schedule Engerix-B(R) and Heplisav-B(R): Data not available. The virus, which is called hepatitis B virus (HBV), can cause lifelong infection, cirrhosis (scarring) of the liver, liver cancer, liver failure, and death. Found inside – Page 278In infants born to hepatitis B surface antigen (HBsAg)-negative mothers, the first dose should be given at hospital ... or the maternal Hep B status is unknown and the infant's weight is less than 2000 g, Hep B vaccine and Hep B immune ... Symptoms of hepatitis B include fever, yellowish skin (jaundice), dark urine, fatigue, nausea, and vomiting. 2008. Background: Antibodies against hepatitis B surface antigen (HBsAg) wane over time following hepatitis B immunisation; hence, it is unclear whether people vaccinated in three-dose or four-dose schedules of the hepatitis B vaccine are still immune when the hepatitis B surface antibody (anti-HBs) level in their body is undetectable, or lower than the level usually considered protective. Thank you for visiting MerckVaccines.com®. The vaccine contains 720 EL.U. doses of Engerix-B and Recombivax HB . Influenza: Annual dose of inactivated influenza vaccine or live attenuated influenza vaccine. Infants are recommended to receive 4 doses of hepatitis B vaccine: 1 dose of monovalent paediatric formulation hepatitis B vaccine at birth ; 3 doses of a paediatric hepatitis B–containing vaccine at 2, 4 and 6 months of age (usually provided as DTPa-hepB-IPV-Hib [diphtheria-tetanus-acellular pertussis, hepatitis B, inactivated poliovirus, Haemophilus influenzae type b]). Renal Dose Adjustments. -Administer hepatitis B immune globulin if appropriate.-Start hepatitis B vaccine as soon as possible after exposure. Hudson, Ohio. Written by an international 'who's who' of hepatology-and now in full color-this new 2nd Edition provides readers with top-notch, authoritative guidance they can count on! Hepatitis B Immunization 3-dose series. Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. This is the third edition of this publication which contains the latest information on vaccines and vaccination procedures for all the vaccine preventable infectious diseases that may occur in the UK or in travellers going outside of the UK ... There must be at least 4 weeks between doses #1 and #2, at least 8 weeks between doses #2 and #3, and at least 16 weeks between doses #1 and #3. Duval B, Gîlca V, Boulianne N et al. Hepatitis B is a contagious liver infection. Hepatitis B vaccine recombinant is made without any human blood or blood products or any other substances of human origin. Use a sterile syringe free of preservatives, antiseptics, and detergents for each reconstitution and injection of VARIVAX because these substances may inactivate the vaccine virus. Immunogenicity of two paediatric doses of monovalent hepatitis B or combined hepatitis A and B vaccine in 8-10-year-old children. Once the vaccine is administered, antibodies are produced to shield the person against the virus. 2003. Dosage, and timing of boosters varies by individual COVID-19 vaccine product. For more news and specials on immunization and vaccines visit the Pink Book's Facebook fan page Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices. Found inside – Page 173Vaccines produced by each manufacturer have been evaluated in clinical trials to determine the agespecific dosage that achieves the maximal seroprotection rate. Persons who respond to hepatitis B vaccine (complete and correct schedule) ... Discard if reconstituted vaccine is not used within 30 minutes. 0.5-mL dose administered subcutaneously on elected date, If administered, 0.5-mL dose a minimum of 3 months after the first dose, 0.5-mL dose to be administered a minimum of 4 weeks after the first dose. Vaccine 2005;23(31):4082-87. Access a companion website at www.netterreference.com featuring the complete searchable text, an Image Bank containing all of the book’s illustrations...downloadable for your personal use, plus 25 printable patient education brochures. Accompanying CD-ROM includes: downloadable image bank of color illustrations for use in presentations ; list of references for each chapter. immunity or immunity from a vaccine, and many immunizations require at least one booster dose, including hepatitis A; hepatitis B; Haemophilus influenzae type B (Hib); measles-mumps-rubella (MMR); tetanus, diphtheria, and pertussis (Tdap); and varicella (chickenpox). Vaccine 2005;23(31):4082-87. The hepatitis B vaccine is recommended for all children, and any adult at an increased risk for getting the hepatitis B virus. The hepatitis B story is more than a fascinating chronicle of a major discovery. What Blumberg followed to the virus was a trail of remarkable "accidents" that happen when scientists seek answers to interesting questions. Dosage and Administration. Hepatitis B Vaccine (Recombinant [Adjuvanted]). Engerix B Injection, Suspension (GlaxoSmithKline Biologicals SA). Heplisav-B demonstrated a statistically significantly higher rate of protection (95%) after one month when compared with Engerix-B (81%) after 6 months. Vaccine 2005;23(31):4082-87. immunity or immunity from a vaccine, and many immunizations require at least one booster dose, including hepatitis A; hepatitis B; Haemophilus influenzae type B (Hib); measles-mumps-rubella (MMR); tetanus, diphtheria, and pertussis (Tdap); and varicella (chickenpox). This site is intended for health care professionals in the United States, its territories, and Puerto Rico. Liver Dose Adjustments Frequently reported (â¥10%) adverse reactions in adolescents and adults ages 13 years and older monitored for up to 42 days include: injection-site complaints: 24.4%; fever â¥100.0°F (37.8°C) oral: 10.2%. Cardell K, Akerlind B, Sallberg M, et al. Wolters Kluwer Clinical Drug Information, Inc. https://online.lexi.com. FitzSimons D, François G, Hall A et al. This drug may cause drowsiness, if affected, do not drive or operate machinery. The Hepatitis B vaccine is a series of inoculations that stimulate the body’s immune system to shield against the Hepatitis B virus.
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